A phase 1b study investigating the safety, tolerability and efficacy of an investigational medicinal product in the treatment of patients with chronic low back pain

Study Type: Phase 1b, multi-centre, industry-sponsored, randomised, double blind, placebo controlled, prospective

Role: Chief Investigator

A Multi-Centre, Prospective, Pragmatic, Randomized, Controlled Clinical Trial to Compare HF10 Therapy to Conventional Medical Management in the Treatment of Non-Surgical Refractory Back Pain

Study Type: Multi-centre Pan-European, industry-sponsored, randomised, prospective

Role: Principal Investigator

A phase 2a, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of an investigational medicinal product as an Adjunctive Therapy in Chronic Complex Regional Pain Syndrome

Study Type: Multi-centre, industry-sponsored, randomised, double blind, placebo-controlled, prospective

Role: Principal Investigator

A Clinical Study to Evaluate HF10™ Therapy in Patients with Chronic Intractable Leg Pain

Study Type: Multi-centre, industry-sponsored, randomised, double blind, placebo-controlled, prospective

Role: Co-investigator

Are Inertial Motion Units (IMU) a potential clinical evaluation tool for individuals with chronic simple low back pain?

Study Type: Academic, prospective collaborative study with the University of Central Lancashire (UCLAN)

Role: Student project supervisor

A qualitative study to explore the decision-making process of clinicians considering spinal cord stimulator trials and permanent implants for chronic pain patients.

Study Type: Academic, funded, qualitative, multi-centre, prospective

Role: Chief investigator

Using patient experiences to develop services for chronic pain.

Study Type: Academic, prospective

Role: Student project supervisor

International Surgical Outcomes Study (ISOS)

Study Type: International, multicentre, observational study comprising 27 countries, sponsored by the Queen Mary University.

Role: Co-investigator

A retrospective study evaluating the trend in the use of opioids in the management of low back pain at RPH between 2010 and 2011

Study Type: Academic, retrospective

Role: Student project supervisor

Should patients be driving soon after starting the neuropathic pain medications? Assessing the effect of a single dose of amitriptyline or pregabalin on sleep, cognitive functioning and driving hazard perception in chronic neuropathic pain patients.

Study Type: Academic, prospective

Role: Student project supervisor

• M Ting, S Tripathi. Time-motion study evaluating the cost of intravenous patient-controlled analgesia: a service evaluation. Anaesthesia 2018; 73(suppl.4): 63
• Peter Outlaw, Shiva Tripathi and Jacqueline Baldwin. Using patient experiences to develop services for chronic pain. British Journal of Pain 2018; 12(2): 122-131
• Bantel C, Tripathi SS, Molony D, Heffernan T, Oomman S, Mehta V and Dickerson S. Prolonged-release oxycodone/naloxone reduces opioid-induced constipation and improves quality of life in laxative-refractory patients: results of an observational study. Clinical and Experimental Gastroenterology 2018; 11: 57–67
• Gareth P. Jones, Shiva S. Tripathi. Oxycodone and Naloxone Combination: A 12-Week Follow-up in 20 Patients Shows Effective Analgesia without Opioid-Induced Bowel Dysfunction. Pain Ther 2016; 5: 107. https://doi.org/10.1007/s40122-016-0051-4
• The International Surgical Outcomes Study group. Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries. British Journal of Anaesthesia 2016; 117 (5): 601–9
• Serpell M, Tripathi S, Scherzinger S, Rojas-Farreras S, Oksche A and Wilson M. Assessment of Transdermal Buprenorphine Patches for the Treatment of Chronic Pain in a UK Observational Study. Patient 2015; DOI 10.1007/s40271-015-0151-y
• Doddrell C and Tripathi S. Successful use of pregabalin by the rectal route to treat chronic neuropathic pain in a patient with complete intestinal failure. BMJ Case Rep 2015. doi:10.1136/bcr-2015- 211511
• Jones GP and Tripathi SS. Successful use of stellate ganglion block and a new centrally acting analgesic with dual mode of action in a resistant temporomandibular joint pain. BMJ Case Rep 2014. doi:10.1136/bcr-2013-203308
• Jones GP, Tripathi SS, Gilbert S, Bradley S, Halshaw C, and Pelech E. Targinact: An effective opioid combination, without the associated bowel problems. in ‘7th world congress world institute of pain’ WIP 2014 Abstract Book, Maastritch The Netherlands, pp. 15
• Tripathi S, Serpell M, Scherzinger S, Rojas-Farreras S, Oksche A and Smith K. 2014. Low incidence of skin irritancies in patients using transdermal buprenorphine (TDB) in ‘7th world congress world institute of pain’ WIP 2014 Abstract Book, Maastritch The Netherlands, pp. 38
• Tripathi SS and Nixon G (2012). Procurement, maintenance and safety of pumps used in acute pain management. In Colvin JR and Peden CJ (3rd ed). Raising the Standard: a compendium of audit recipes for continuous quality improvement in anaesthesia. London. The Royal College of Anaesthetists: 11.3: 316-17
• Rastogi S and Tripathi S. Cardiac arrest following stellate ganglion block performed under ultrasound guidance. Anaesthesia 2010; 65: 1042
• Tripathi SS, Hunter JM. Neuromuscular blocking drugs in the critically ill. Continuing Education in Anaesthesia Critical Care and Pain 2006; 6(3): 119-123. This article was reprinted in the Indian edition of Continuing Education in Anaesthesia Critical Care and Pain 2006; 1(3): 72-76
• Tripathi SS, Sprigge J. Twenty-eight cases of failure to intubate in 8132 obstetric general anaesthetics for more than 22 yr. Br J Anaesth 2006; 96: 287
• Tripathi SS. Book review. Pentothal Postcards by DC Lai. Br J Anaesth 2005; 95: 843
• Kumar A, Tripathi SS, Dhar D. A case of reversible paraparesis following coeliac plexus block. Reg Anesth Pain Med. 2001; 26: 75-78
• Kumar A, Dhar D, Tripathi SS. Pain Management in ICU. Hospital Today 2000; 5: 79 – 84